CSTF2 and CEACAM6

Data Source:
BioGRID (two hybrid)

		CSTF2	CEACAM6
Description		cleavage stimulation factor subunit 2	CEA cell adhesion molecule 6
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GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Neutrophil Degranulation Leukocyte Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS			Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		49 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN2 UBQLN4 UFSP1 USP54 ZNF341	32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76
Entrez ID		1478	4680
HPRD ID		02652	01233
Ensembl ID		ENSG00000101811	ENSG00000086548
Uniprot IDs		B3V096 B4DUD5 E7EWR4 P33240	P40199
PDB IDs		1P1T 2J8P 6Q2I 6TZE	4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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