CSTF2 and CSTF3

Data Source:
BioGRID (biochemical, pull down, affinity chromatography technology, biochemical)
HPRD (in vitro)

		CSTF2	CSTF3
Description		cleavage stimulation factor subunit 2	cleavage stimulation factor subunit 3
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GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body	Nucleus Nucleoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage RNA 3'-end Processing MRNA 3'-end Processing
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Anger ( 24489884) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		49 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN2 UBQLN4 UFSP1 USP54 ZNF341	13 interacting genes: CSTF1 CSTF2 MIR128-2 MIR138-2 MIR15B MIR19A MIR19B1 MIR21 MIR92A2 MIRLET7A3 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		1478	1479
HPRD ID		02652	02651
Ensembl ID		ENSG00000101811	ENSG00000176102
Uniprot IDs		B3V096 B4DUD5 E7EWR4 P33240	Q12996
PDB IDs		1P1T 2J8P 6Q2I 6TZE	6B3X 6URO
Enriched GO Terms of Interacting Partners?
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