CSH1 and SGTB

Data Source:
BioGRID (two hybrid)

		CSH1	SGTB
Description		chorionic somatomammotropin hormone 1	small glutamine rich tetratricopeptide repeat co-chaperone beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endosome Lumen Vesicle	Membrane TRC Complex
	Molecular Function	Growth Hormone Receptor Binding Hormone Activity Protein Binding Growth Factor Activity Metal Ion Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Response To Nutrient Levels Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Growth Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Animal Organ Development Growth Hormone Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding
Pathways		Prolactin receptor signaling Prolactin receptor signaling Growth hormone receptor signaling
Drugs
Diseases
GWAS		Height ( 25429064 23563607 31562340)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: PRLR PSMD9 PTPN12 SGTB SMAD2 SMAD4 SMAD9	116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B
Entrez ID		1442	54557
HPRD ID		08350	18049
Ensembl ID		ENSG00000136488	ENSG00000197860
Uniprot IDs		A8K6C2 P0DML2 P0DML3	Q96EQ0
PDB IDs		1Z7C
Enriched GO Terms of Interacting Partners?
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