SESN3 and MIOS

Data Source:
BioGRID (pull down)

		SESN3	MIOS
Description		sestrin 3	meiosis regulator for oocyte development
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm TORC2 Complex GATOR2 Complex	Nucleoplasm Cytoplasm Lysosomal Membrane Cytosol Cell Junction GATOR2 Complex
	Molecular Function	Protein Binding Oxidoreductase Activity, Acting On Peroxide As Acceptor Leucine Binding	Protein Binding
	Biological Process	Positive Regulation Of Macroautophagy Response To Insulin Cellular Response To Amino Acid Starvation TORC2 Signaling Cellular Response To Glucose Starvation Glucose Homeostasis Regulation Of Insulin Receptor Signaling Pathway Regulation Of Protein Kinase B Signaling Cellular Response To Leucine Regulation Of Response To Reactive Oxygen Species Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein-containing Complex Localization
Pathways		TP53 Regulates Metabolic Genes	Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Chronotype ( 30696823) Common carotid intima-media thickness ( 29206233) Common carotid intima-media thickness in HIV infection ( 29206233) Diastolic blood pressure ( 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		4 interacting genes: MIOS NPRL3 WDR24 WDR59	3 interacting genes: NTAQ1 SESN1 SESN3
Entrez ID		143686	54468
HPRD ID		09682	07898
Ensembl ID		ENSG00000149212	ENSG00000164654
Uniprot IDs		P58005	A0A024RA24 Q9NXC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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