MPP7 and HSBP1

Data Source:
BioGRID (two hybrid)

		MPP7	HSBP1
Description		membrane palmitoylated protein 7	heat shock factor binding protein 1
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GO Annotations	Cellular Component	Nucleoplasm Adherens Junction Bicellular Tight Junction Cell Cortex Lateral Plasma Membrane Cell Junction MPP7-DLG1-LIN7 Complex	Nucleus Nucleoplasm Cytosol Cytoskeleton
	Molecular Function	Protein Binding Protein Domain Specific Binding Signaling Adaptor Activity Cadherin Binding Molecular Adaptor Activity	Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Establishment Of Cell Polarity Positive Regulation Of Protein-containing Complex Assembly Bicellular Tight Junction Assembly Protein Localization To Adherens Junction	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat
Pathways			HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Bone mineral density ( 24249740) Bone mineral density (paediatric, skull) ( 24945404) Diverticular disease ( 30177863) Glaucoma (primary open-angle) ( 27001270) Heel bone mineral density ( 30598549 28869591) Hippocampal volume ( 21116278) Lumbar spine bone mineral density ( 29499414 22504420) Macular thickness ( 30535121) Obesity-related traits ( 23251661) Psychosis and Alzheimer's disease ( 22005930)	Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		7 interacting genes: DLGAP4 HSBP1 LIN7A LIN7B LIN7C MYSM1 TRIM5	21 interacting genes: BLOC1S5 BRK1 CCHCR1 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 WASHC1 WASHC3 ZBTB25
Entrez ID		143098	3281
HPRD ID		14733	05185
Ensembl ID		ENSG00000150054	ENSG00000230989
Uniprot IDs		Q5T2T1	O75506
PDB IDs		3LRA 3O46	3CI9
Enriched GO Terms of Interacting Partners?
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