HSBP1 and WASHC1

Data Source:
BioGRID (two hybrid)

		HSBP1	WASHC1
Description		heat shock factor binding protein 1	WASH complex subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cytoskeleton	Exocyst Early Endosome Late Endosome Autophagosome Centriole Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane WASH Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding	Actin Binding Protein Binding Ubiquitin Protein Ligase Binding Alpha-tubulin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat	Exocytosis Negative Regulation Of Autophagy Protein Transport Endosomal Transport Extracellular Matrix Disassembly Positive Regulation Of Cell Migration Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Ubiquitination Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi Negative Regulation Of Phosphatidylinositol 3-kinase Activity Retrograde Transport, Endosome To Plasma Membrane
Pathways		HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS		Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		21 interacting genes: BLOC1S5 BRK1 CCHCR1 CYSRT1 GORASP2 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 LNX1 MPP7 NOTCH2NLA SDCBP SDCBP2 WASHC1 WASHC3 ZBTB25	54 interacting genes: ABI2 ABI3 ATPAF2 BECN1 BLOC1S2 C14orf119 C1orf216 CDR2L CEP55 EIF3F EXOC8 FHL2 GYS1 HGS HSBP1 HSF2BP IFT57 KANK2 KLC3 KRT20 KRT26 KRT28 KRT3 KRT75 KRT76 LIMK1 LMO1 LMO2 LMO3 LMO4 MORN4 MRFAP1 NDC80 NUP62CL OIP5 OSTF1 POLR1C PRKAA2 RABGEF1 RNF2 SDCBP SMARCD1 TPM1 TPM3 TRIM69 TSG101 TTC19 TXLNA UBL5 USP20 WASHC3 WASHC4 WASHC5 ZBTB16
Entrez ID		3281	100287171
HPRD ID		05185
Ensembl ID		ENSG00000230989	ENSG00000181404
Uniprot IDs		O75506	A8K0Z3
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?
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