CRHR2 and UCN3

Data Source:
HPRD (two hybrid, in vitro)

		CRHR2	UCN3
Description		corticotropin releasing hormone receptor 2	urocortin 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Axon Terminus	Extracellular Region Extracellular Space Varicosity Axon Terminus
	Molecular Function	Protein Binding G Protein-coupled Peptide Receptor Activity Corticotrophin-releasing Factor Receptor Activity Peptide Hormone Binding Corticotropin-releasing Hormone Receptor Activity	Hormone Activity Corticotropin-releasing Hormone Receptor Binding Corticotropin-releasing Hormone Receptor 2 Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Hormone-mediated Signaling Pathway Long-term Synaptic Potentiation Cellular Response To Corticotropin-releasing Hormone Stimulus	Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Digestion Response To Glucose Hormone-mediated Signaling Pathway Cellular Response To Nutrient Levels Positive Regulation Of Insulin Secretion Response To Immobilization Stress Response To Starvation Positive Regulation Of Membrane Potential Response To Corticosterone Cellular Response To Hypoxia
Pathways		G alpha (s) signalling events Synthesis, secretion, and deacylation of Ghrelin ADORA2B mediated anti-inflammatory cytokines production	Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Type 2 diabetes ( 24509480 30297969)	Intelligence ( 22449649)
Interacting Genes		7 interacting genes: APP CRH GPR35 MALL UCN UCN2 UCN3	3 interacting genes: CRHR1 CRHR2 IL10RB
Entrez ID		1395	114131
HPRD ID		03614	12066
Ensembl ID		ENSG00000106113	ENSG00000178473
Uniprot IDs		A0A090N7T4 Q13324	Q969E3
PDB IDs		3N93 3N95 3N96 6PB1	2RMH 3N93
Enriched GO Terms of Interacting Partners?
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