FUNDC1 and SLC25A46

Data Source:
BioGRID (two hybrid)

		FUNDC1	SLC25A46
Description		FUN14 domain containing 1	solute carrier family 25 member 46
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Autophagy Of Mitochondrion Response To Hypoxia Response To Organonitrogen Compound Macroautophagy	Mitochondrial Membrane Fission
Pathways		Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851 30929738 27182965 31619474 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cardiac structure and function ( 19584346) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Uterine fibroid size (maximum volume) ( 30196971)
Interacting Genes		15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1	16 interacting genes: AQP6 FHL3 FUNDC1 HSD17B11 HSD17B13 LEPROTL1 MFSD14B ODF4 REEP2 REEP4 SLC10A1 SLC10A6 SLC66A2 SLC7A8 SPCS1 VMA21
Entrez ID		139341	91137
HPRD ID		06658	14283
Ensembl ID		ENSG00000069509	ENSG00000164209
Uniprot IDs		Q8IVP5	B4DY98 Q96AG3
PDB IDs		2N9X 5GMV
Enriched GO Terms of Interacting Partners?
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