FUNDC1 and MARCHF5

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		FUNDC1	MARCHF5
Description		FUN14 domain containing 1	membrane associated ring-CH-type finger 5
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding GTPase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Autophagy Of Mitochondrion Response To Hypoxia Response To Organonitrogen Compound Macroautophagy	Protein Polyubiquitination Protein Autoubiquitination Protein Localization To Mitochondrion Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cell Aging
Pathways		Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)
Interacting Genes		15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1	39 interacting genes: AKTIP ANKS6 AQP6 BIK BNIP1 CGRRF1 CREB3 ERGIC3 FATE1 FIS1 FUNDC1 GPX8 HSD17B13 MANBAL MAP1B MFN2 ODF4 PTPN5 RTN4IP1 SAR1A SCD SGPL1 SOD1 STMN4 TANK TIMMDC1 TMEM139 TMEM14B UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2I UBE2N UBE2T UBE2W UTRN YIF1A
Entrez ID		139341	54708
HPRD ID		06658	07909
Ensembl ID		ENSG00000069509	ENSG00000198060
Uniprot IDs		Q8IVP5	Q9NX47
PDB IDs		2N9X 5GMV
Enriched GO Terms of Interacting Partners?
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