PIP5KL1 and PIP5K1A

Data Source:
HPRD (in vivo)

		PIP5KL1	PIP5K1A
Description		phosphatidylinositol-4-phosphate 5-kinase like 1	phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Cell Projection	Nucleus Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex Plasma Membrane Focal Adhesion Nuclear Speck Lamellipodium Ruffle Membrane
	Molecular Function	ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Kinase Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Phosphatidylinositol Phosphorylation	Glycerophospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phagocytosis Signal Transduction Phospholipid Biosynthetic Process Fibroblast Migration Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Migration Keratinocyte Differentiation Actin Cytoskeleton Reorganization Phosphatidylinositol Phosphorylation Focal Adhesion Assembly Cell Chemotaxis Protein Localization To Plasma Membrane Activation Of GTPase Activity Ruffle Assembly
Pathways			Synthesis of PIPs at the plasma membrane PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Body mass index ( 26426971)
Interacting Genes		2 interacting genes: PIP5K1A PIP5K1B	16 interacting genes: APP ARF1 ARF5 ARF6 BTK CADPS CASP3 KRAS MIR140 MIR34B NEDD4 PIP5KL1 PLD1 PLD2 RHOU TEC
Entrez ID		138429	8394
HPRD ID		15139	04470
Ensembl ID		ENSG00000167103	ENSG00000143398
Uniprot IDs		Q5T9C9	A6PW57 Q99755
PDB IDs
Enriched GO Terms of Interacting Partners?
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