CR2 and FHOD1

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		CR2	FHOD1
Description		complement C3d receptor 2	formin homology 2 domain containing 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Receptor Complex Extracellular Exosome	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Intercalated Disc Membrane Bleb
	Molecular Function	Virus Receptor Activity Complement Binding DNA Binding Complement Receptor Activity Transmembrane Signaling Receptor Activity Protein Binding Protein Homodimerization Activity	Protein Binding Protein Domain Specific Binding Identical Protein Binding Protein Self-association Actin Filament Binding
	Biological Process	Complement Receptor Mediated Signaling Pathway Immune Response Complement Activation, Alternative Pathway Complement Activation, Classical Pathway B Cell Differentiation Regulation Of Complement Activation B Cell Proliferation Viral Entry Into Host Cell	Nuclear Migration Cortical Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Actin Filament Network Formation Establishment Of Centrosome Localization
Pathways		Regulation of Complement cascade
Drugs
Diseases
GWAS		Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717) Refractive error ( 32231278) Systemic sclerosis ( 29293537) Type 2 diabetes ( 21490949)
Interacting Genes		10 interacting genes: ANXA6 C3 CD19 CR1 FCER2 FHOD1 HNRNPU IFITM1 IFNA1 TP53	22 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 TRIM21 YWHAZ ZMYND8
Entrez ID		1380	29109
HPRD ID		00399	06049
Ensembl ID		ENSG00000117322	ENSG00000135723
Uniprot IDs		P20023	A0A068F7M9 Q9Y613
PDB IDs		1GHQ 1LY2 1W2R 1W2S 2ATY 2GSX 3OED	3DAD
Enriched GO Terms of Interacting Partners?
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