ASZ1 and TMEM218

Data Source:
BioGRID (two hybrid)

		ASZ1	TMEM218
Description		ankyrin repeat, SAM and basic leucine zipper domain containing 1	transmembrane protein 218
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Pi-body	Cilium Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Male Meiotic Nuclear Division Multicellular Organism Development Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation
Pathways		PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Esophageal adenocarcinoma ( 27527254) Waist circumference ( 23966867) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		10 interacting genes: BET1 C14orf180 DEFB127 LPAR3 SLC35A1 SMIM1 TMEM218 TMEM97 TNFRSF10C TSPO2	72 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR
Entrez ID		136991	219854
HPRD ID		10677	19054
Ensembl ID		ENSG00000154438	ENSG00000150433
Uniprot IDs		Q8WWH4	A2RU14
PDB IDs
Enriched GO Terms of Interacting Partners?
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