CPE and NTS

Data Source:
HPRD (in vivo)

		CPE	NTS
Description		carboxypeptidase E	neurotensin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome	Extracellular Region Transport Vesicle Intracellular Membrane-bounded Organelle Axon Terminus
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding	Neuropeptide Hormone Activity Protein Binding Receptor Ligand Activity Neuropeptide Receptor Binding
	Biological Process	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway
Pathways		Insulin processing	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Insulin human Insulin pork
Diseases
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Metabolite levels ( 23823483)
Interacting Genes		18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A	10 interacting genes: ACE2 ARRB2 CPE MEP1A MFF NLN NTSR1 NTSR2 PREP SORT1
Entrez ID		1363	4922
HPRD ID		00272	08878
Ensembl ID		ENSG00000109472	ENSG00000133636
Uniprot IDs		A0A384N679 P16870	P30990 Q6FH20
PDB IDs			2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ 6UP7
Enriched GO Terms of Interacting Partners?
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