TMEM139 and CYB5B

Data Source:
BioGRID (two hybrid)

		TMEM139	CYB5B
Description		transmembrane protein 139	cytochrome b5 type B
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Mitochondrial Outer Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding	Protein Binding Enzyme Activator Activity Electron Transfer Activity Heme Binding Metal Ion Binding Nitrite Reductase (NO-forming) Activity
	Biological Process		Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Electron Transport Chain Regulation Of Catalytic Activity
Pathways			Phase I - Functionalization of compounds
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS			Blood osmolality (transformed sodium) ( 28360221) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 26426971) Heel bone mineral density ( 30598549) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		39 interacting genes: ABHD16A AGTRAP APOL2 ATP6V0C BCL2L2 CD151 CDS2 CLN6 CMTM5 CTSA CXCL16 CYB5B FAXDC2 KCNK1 MALL MARCHF5 MIP NAPB NINJ2 NKG7 NSG1 PLPP4 PMP22 SEC22B SFTPC SLC30A8 SLC35A1 SMCO4 SMURF2 TMEM107 TMEM120B TMEM19 TMEM60 TRAF3IP3 UBIAD1 UPK1B VAMP5 YIF1A ZFPL1	48 interacting genes: AHNAK2 APP AQP6 BIK BNIP3L BTNL9 CD33 CD79A CGRRF1 CLDN7 CLN8 CPLX4 CREB3 EBP FAM209A FAM210B FNDC9 FRMD3 GJB5 GPR152 IGSF9 KCNK5 KIR2DL3 LMNA MARCHF8 MFF MFSD14B MFSD4B MFSD5 MUC1 NDUFAF2 PDZK1IP1 PHACTR3 PLPP4 REEP4 RETREG3 SDHAF4 SLC10A6 SLC16A2 SLC39A9 STOM STX1A SYT1 TMEM139 TMEM237 TMEM35A TMEM41A TMEM86B
Entrez ID		135932	80777
HPRD ID		08298	13106
Ensembl ID		ENSG00000178826	ENSG00000103018
Uniprot IDs		Q8IV31	O43169
PDB IDs			3NER
Enriched GO Terms of Interacting Partners?
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