ZNF513 and PPARGC1B

Data Source:
BioGRID (two hybrid)

		ZNF513	PPARGC1B
Description		zinc finger protein 513	PPARG coactivator 1 beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Mitochondrion Cytosol Mediator Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding Protein Binding Metal Ion Binding	Transcription Coregulator Activity RNA Binding Transcription Factor Binding Estrogen Receptor Binding Nuclear Receptor Coactivator Activity AF-2 Domain Binding
	Biological Process	Visual Perception Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus Retina Development In Camera-type Eye	Ossification Regulation Of Transcription, DNA-templated Mitochondrial Transcription Actin Filament Organization Positive Regulation Of Alkaline Phosphatase Activity Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Positive Regulation Of Phosphorylation Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Bone Resorption Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To CAMP Bone Trabecula Formation Positive Regulation Of Cold-induced Thermogenesis
Pathways			PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Transcriptional activation of mitochondrial biogenesis Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity
Drugs			Amiodarone
Diseases		Retinitis pigmentosa (RP)
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) L-selectin levels ( 25576479) Non-oily fish consumption ( 32066663)	Age spots ( 29895819) Apolipoprotein A1 levels ( 32203549) Basal cell carcinoma ( 31174203) Cutaneous malignant melanoma ( 32341527) Deep white matter hyperintensities ( 32517579) Electrocardiographic traits ( 32602732) Facial pigmentation measurement (polar light) ( 32835660) Facial pigmentation measurement (UV light) ( 32835660) Freckles ( 29895819) HDL cholesterol levels ( 32203549) Keratinocyte cancer (MTAG) ( 31174203) Low tan response ( 29739929) Nevus count ( 30429480) Nevus count or cutaneous melanoma ( 30429480) Obesity-related traits ( 23251661) Tanning ( 19340012) Vitiligo ( 27723757)
Interacting Genes		5 interacting genes: DNMT3A KAT5 PPARGC1B ZFP64 ZZZ3	13 interacting genes: AKT1 ESR1 ESRRG HCFC1 HNF4A PPARA SRC THRB ZBTB9 ZFP64 ZNF200 ZNF212 ZNF513
Entrez ID		130557	133522
HPRD ID		15813	10594
Ensembl ID		ENSG00000163795	ENSG00000155846
Uniprot IDs		Q8N8E2	B7ZM40 Q86YN6
PDB IDs			3SP6 6D0Y
Enriched GO Terms of Interacting Partners?
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