UHMK1 and RGS8

Data Source:
BioGRID (two hybrid)

		UHMK1	RGS8
Description		U2AF homology motif kinase 1	regulator of G protein signaling 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Axon Midbody Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule	Nucleus Plasma Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Neuronal Cell Body Membrane Perikaryon Synapse
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transferase Activity Ribonucleoprotein Complex Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Cell Cycle Arrest Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Protein Autophosphorylation Regulation Of Protein Export From Nucleus	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Dopamine Receptor Signaling Pathway
Pathways		Estrogen-dependent nuclear events downstream of ESR-membrane signaling	G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)	Morning person ( 30696823)
Interacting Genes		9 interacting genes: C1orf109 DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP	7 interacting genes: ADRB2 CCDC85B GOLGA2 HOOK2 KRT40 PLEKHF2 UHMK1
Entrez ID		127933	85397
HPRD ID		12318	06221
Ensembl ID		ENSG00000152332	ENSG00000135824
Uniprot IDs		Q8TAS1	P57771
PDB IDs			2IHD 2ODE 5DO9
Enriched GO Terms of Interacting Partners?
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