UHMK1 and DEPDC1B

Data Source:
BioGRID (two hybrid)

		UHMK1	DEPDC1B
Description		U2AF homology motif kinase 1	DEP domain containing 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Axon Midbody Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule	Cytosol
	Molecular Function	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transferase Activity Ribonucleoprotein Complex Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	GTPase Activator Activity
	Biological Process	Cell Cycle Arrest Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Protein Autophosphorylation Regulation Of Protein Export From Nucleus	Cell Migration Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Rho GTPase cycle
Drugs
Diseases
GWAS		Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		9 interacting genes: C1orf109 DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP	6 interacting genes: CDC23 EBPL GRIP1 PTPRF RGS3 UHMK1
Entrez ID		127933	55789
HPRD ID		12318	16794
Ensembl ID		ENSG00000152332	ENSG00000035499
Uniprot IDs		Q8TAS1	Q8WUY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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