CCR4 and CDK10

Data Source:
BioGRID (two hybrid)

		CCR4	CDK10
Description		C-C motif chemokine receptor 4	cyclin dependent kinase 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Neuronal Cell Body	Nucleus Cytoplasm Ciliary Basal Body
	Molecular Function	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding	Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Neuron Migration Tolerance Induction Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Radiation Response To Bacterium Calcium-mediated Signaling Response To Antibiotic Homeostasis Of Number Of Cells Positive Regulation Of Positive Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway	Protein Phosphorylation Traversing Start Control Point Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Peptidyl-threonine Phosphorylation Cell Projection Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of MAPK Cascade Negative Regulation Of Cilium Assembly
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Mogamulizumab FLX475
Diseases
GWAS		Asthma ( 31959851) Celiac disease ( 22057235 20190752) Multiple sclerosis ( 24076602) Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (perceptual aberration scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (revised physical anhedonia scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (revised social anhedonia scale) ( 28525603)	Blond vs. brown/black hair color ( 30531825) Brain morphology (MOSTest) ( 32665545) Brown vs. black hair color ( 30531825) Cutaneous malignant melanoma ( 32341527) Height ( 25429064) Hemoglobin levels ( 32327693) Intake of total sugars ( 31005972) Melanoma ( 28212542) Red vs. brown/black hair color ( 30531825)
Interacting Genes		37 interacting genes: ATP2A2 B3GAT3 BSG CACNA1H CCKBR CCL17 CCL22 CCL3 CCL5 CDK10 CH25H CLASP2 CLPTM1 CNTNAP1 DHCR24 ERGIC3 FAM234A FXR2 GHITM GRK2 GRK3 NAT14 NDRG2 NSUN2 PKM PRDX1 PTOV1 RTN1 RTN4 SLC12A5 SLC3A2 SLCO4A1 STIMATE SYNGR2 TMEM101 TMEM11 TRARG1	4 interacting genes: CCR4 ETS2 FBXO7 RNF115
Entrez ID		1233	8558
HPRD ID		05324	04588
Ensembl ID		ENSG00000183813	ENSG00000185324
Uniprot IDs		A0N0Q1 P51679	B7Z537 Q15131
PDB IDs
Enriched GO Terms of Interacting Partners?
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