AP3S1 and RUFY1

Data Source:
BioGRID (pull down)

		AP3S1	RUFY1
Description		adaptor related protein complex 3 subunit sigma 1	RUN and FYVE domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Axon Cytoplasm	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		Golgi Associated Vesicle Biogenesis	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		7 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		1176	80230
HPRD ID		03298	15282
Ensembl ID		ENSG00000177879	ENSG00000176783
Uniprot IDs		F5H459 Q92572	A8K7B1 Q96T51
PDB IDs			2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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