RUFY1 and AP3M1

Data Source:
BioGRID (pull down)

		RUFY1	AP3M1
Description		RUN and FYVE domain containing 1	adaptor related protein complex 3 subunit mu 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Axon Cytoplasm
	Molecular Function	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding	Protein Binding Small GTPase Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis	Protein Targeting To Lysosome Endocytosis Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Synthesis of PIPs at the plasma membrane	Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)	Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25	15 interacting genes: AGTRAP AQP4 ARNT2 CRMP1 DVL3 IL36RN RSPH14 RUFY1 SIPA1L2 SLC12A4 SPAG16 TGOLN2 TRIM14 TRIM23 TRIM9
Entrez ID		80230	26985
HPRD ID		15282	16496
Ensembl ID		ENSG00000176783	ENSG00000185009
Uniprot IDs		A8K7B1 Q96T51	A0A024QZR5 B4DRN6 Q9Y2T2
PDB IDs		2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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