RFFL and OPTN

  • Data Source:
  • BioGRID (enzymatic study)

RFFL

OPTN

Description ring finger and FYVE like domain containing E3 ubiquitin protein ligase optineurin
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute post-radiotherapy pain in breast cancer ( 31196165)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Night sleep phenotypes ( 27126917)
  • QT interval ( 19305408)
Interacting Genes 21 interacting genes: ATXN3 ATXN3L EHD1 ESPL1 MICALL1 OPTN OTUB1 OTUB2 RAB11FIP1 SFN STAM UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2N UBE2V2 UCHL5 USP28 USP5 USP7 69 interacting genes: AIMP1 ARRDC3 ATG16L1 ATG5 CALM1 CCDC13 CDC23 CLTC CMYA5 DAZAP2 DYSF DZIP1 FAM189A2 FLII FOS FTH1 GABARAP GABARAPL1 GABARAPL2 GNAS GRM1 GTF3A HACE1 HSF2BP HSPB1 HTT IRAK1 KANSL1L LITAF LNX2 MAP1LC3A MAP1LC3C MPP1 MYH3 MYO6 PIAS4 PICK1 POU6F2 RAB11A RAB11B RAB12 RAB14 RAB25 RAB8A RBM12 RFFL RNF11 RNF216 SDCBP SLF2 SNX6 TBC1D15 TBC1D17 TNIP1 UBB UBC UQCRQ USP2 VCP WASHC3 WIPI2 ZNF17 ZNF181 ZNF302 ZNF329 ZNF398 ZNF426 ZNF670 ZNF711
Entrez ID 117584 10133
HPRD ID 11489 03891
Ensembl ID ENSG00000092871 ENSG00000123240
Uniprot IDs Q8WZ73 Q96CV9
PDB IDs 1Y02 2LO4 2LUE 3VTV 3VTW 5AAZ 5B83 5EOA 5EOF
Enriched GO Terms of Interacting Partners?
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