FCRL3 and SLC30A3

Data Source:
BioGRID (two hybrid)

		FCRL3	SLC30A3
Description		Fc receptor like 3	solute carrier family 30 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface	Cytoplasm Lysosomal Membrane Endosome Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Synaptic Vesicle Membrane Late Endosome Membrane Neuron Projection Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity Kinase Binding Phosphatase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding ABC-type Zinc Transporter Activity
	Biological Process	Negative Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import Positive Regulation Of Protein Serine/threonine Phosphatase Activity	Response To Zinc Ion Positive Regulation Of Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle
Pathways			Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Graves' disease ( 21841780) IgA nephropathy ( 26028593) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 31604244 21833088) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)	Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: AGPAT4 CMTM5 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70	28 interacting genes: AP3B1 AP3D1 AP3S1 CD40 CGRRF1 DNAJC5 ELOVL4 FCRL3 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 OCIAD1 RETREG3 RNF19B RTN3 SCN3B SGPL1 SLC10A6 SLC30A8 SLC34A2 SLC35C2 TMEM14B TMEM242
Entrez ID		115352	7781
HPRD ID		07352	11924
Ensembl ID		ENSG00000160856	ENSG00000115194
Uniprot IDs		Q96P31	B4DXX8 Q99726
PDB IDs
Enriched GO Terms of Interacting Partners?
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