SLC30A3 and HSD17B13

Data Source:
BioGRID (two hybrid)

		SLC30A3	HSD17B13
Description		solute carrier family 30 member 3	hydroxysteroid 17-beta dehydrogenase 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endosome Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Synaptic Vesicle Membrane Late Endosome Membrane Neuron Projection Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding ABC-type Zinc Transporter Activity	Molecular_function Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Response To Zinc Ion Positive Regulation Of Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle	Lipid Droplet Organization Positive Regulation Of Lipid Biosynthetic Process
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Lipid particle organization
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Bulimia nervosa ( 23568457) Liver enzyme levels (alanine transaminase) ( 22001757) Nonalcoholic steatohepatitis ( 32298765) Platelet count ( 22139419) Rosacea symptom severity ( 29771307) Triglyceride levels ( 31928498)
Interacting Genes		28 interacting genes: AP3B1 AP3D1 AP3S1 CD40 CGRRF1 DNAJC5 ELOVL4 FCRL3 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 OCIAD1 RETREG3 RNF19B RTN3 SCN3B SGPL1 SLC10A6 SLC30A8 SLC34A2 SLC35C2 TMEM14B TMEM242	118 interacting genes: ABHD16A ADGRE2 AGPAT3 AGPAT4 AGTRAP AIG1 ANKRD46 AOC3 APOA2 ARL6IP1 ATP6V0C BBC3 BRICD5 C3orf52 CACNG1 CALHM6 CCDC167 CDIPT CLDN10 CLDN19 CLDN4 CLDND2 CMTM5 CMTM7 CYB5R3 CYBC1 CYP4F2 DIABLO EBP ECPAS FATE1 FAXDC2 FETUB GJB2 GOLM1 GOSR2 GYPB HSD3B7 IGFBP5 INSIG2 ITGAM JAGN1 LPCAT2 LRAT MARCHF5 MFSD5 MGLL MIEF2 MMP14 MOSPD3 MS4A1 NAPB NAT8 NRM ORMDL3 PBX3 PLIN3 PLN PLP2 PNLIPRP1 PTPN9 RABAC1 REEP6 RHOU RPRM RUSF1 SACM1L SCAMP5 SCARF1 SCD SEC22B SERP1 SFT2D2 SFXN1 SFXN2 SFXN3 SLC25A46 SLC30A3 SLC35B4 SLC35E4 SMIM1 SNORC SPG21 ST6GAL2 STRIT1 STX5 STX7 TBRG4 TF THSD7A TIMM23 TIMMDC1 TMEM100 TMEM120A TMEM140 TMEM14C TMEM167B TMEM19 TMEM203 TMEM222 TMEM229B TMEM243 TMEM255B TMEM31 TMEM42 TMEM60 TMEM86B TMEM97 TMX2 TPRG1 TREX1 UBXN8 UNC50 VAMP2 VAPA VAPB YIPF2 YIPF4
Entrez ID		7781	345275
HPRD ID		11924	18023
Ensembl ID		ENSG00000115194	ENSG00000170509
Uniprot IDs		B4DXX8 Q99726	Q7Z5P4
PDB IDs
Enriched GO Terms of Interacting Partners?
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