C1QTNF2 and KCNIP3

Data Source:
BioGRID (two hybrid)

		C1QTNF2	KCNIP3
Description		C1q and TNF related 2	potassium voltage-gated channel interacting protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Protein-DNA Complex Axon Terminus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity Ion Channel Binding
	Biological Process	Regulation Of Lipid Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Intracellular Protein Transport Apoptotic Process Signal Transduction Cardiac Conduction Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport
Pathways			Phase 1 - inactivation of fast Na+ channels
Drugs
Diseases
GWAS		Weight loss (gastric bypass surgery) ( 23643386)	Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		24 interacting genes: ANKRD11 BANP C1orf109 CHIC2 GPANK1 HPCA HPCAL1 KCNIP3 KLHL12 LCK LGALS14 MTX2 NCALD NCS1 NOL4 P4HA3 PHOSPHO2 TCEANC TIMM8A TRIM54 UBQLN1 UBQLN2 USP20 VSNL1	26 interacting genes: ASPH C1QTNF2 CALM2 CASP3 CD177 CDSN CLN3 CREB1 CREM CTBP2 GOLGA7 GRK2 GRK6 IGF1R IGLV3-25 IL6ST KHDC4 MAVS PCBD2 PPP3CA PSEN1 PSEN2 SOD3 SRL TARBP2 ZG16
Entrez ID		114898	30818
HPRD ID		12715	05232
Ensembl ID		ENSG00000145861	ENSG00000115041
Uniprot IDs		A0A3B0INC0 A0A499FIM1 Q9BXJ5	A0A024RE22 Q9Y2W7
PDB IDs			2E6W
Enriched GO Terms of Interacting Partners?
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