GABARAP and SNX18

Data Source:
BioGRID (pull down)

		GABARAP	SNX18
Description		GABA type A receptor-associated protein	sorting nexin 18
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Lysosome Autophagosome Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Cytoplasmic Vesicle Cell Body Synapse Perinuclear Region Of Cytoplasm Sperm Midpiece	Endosome Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Autophagosome Assembly Microtubule Cytoskeleton Organization Autophagy Of Mitochondrion Protein Targeting Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Macroautophagy Autophagosome Maturation	Mitotic Cytokinesis Endocytosis Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity
Pathways		Macroautophagy TBC/RABGAPs	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		57 interacting genes: AMBRA1 ANK2 ANK3 ATG101 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 ATXN3 BIRC6 CUL3 DMPK DVL2 FLCN GABRG1 GABRG2 GABRG3 GPHN HDAC5 KBTBD7 KDR LMNB1 MAPK15 MEFV MIB1 MLH1 MPC1 MYBPC2 NBR1 NEDD4 NSF OPTN PCM1 PGS1 PKP4 RB1CC1 SEC62 SNX18 SQSTM1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TLE5 TP53INP1 TRIM21 TRIM32 TSR2 TTN TUBB3 ULK1 ULK2 VPS28	19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42
Entrez ID		11337	112574
HPRD ID		05496	15407
Ensembl ID		ENSG00000170296	ENSG00000178996
Uniprot IDs		O95166 Q6IAW1	Q96RF0
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO 7BRQ 7BRT 7BRU 7BV4
Enriched GO Terms of Interacting Partners?
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