CHRM5 and SLC5A6

Data Source:
BioGRID (two hybrid)

		CHRM5	SLC5A6
Description		cholinergic receptor muscarinic 5	solute carrier family 5 member 6
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse Postsynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity	Sodium-dependent Multivitamin Transmembrane Transporter Activity Biotin Transmembrane Transporter Activity Pantothenate Transmembrane Transporter Activity Symporter Activity
	Biological Process	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway	Biotin Metabolic Process Sodium Ion Transport Biotin Transport Pantothenate Transmembrane Transport Pantothenate Metabolic Process Transmembrane Transport Transport Across Blood-brain Barrier Biotin Import Across Plasma Membrane
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules
Drugs		Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil	Lipoic acid
Diseases
GWAS		Malaria ( 31844061)	Blood metabolite levels ( 24816252) Fasting blood glucose adjusted for BMI ( 25625282)
Interacting Genes		31 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33	4 interacting genes: CHRM5 ERBIN GALNT6 UBC
Entrez ID		1133	8884
HPRD ID		00331	04934
Ensembl ID		ENSG00000184984	ENSG00000138074
Uniprot IDs		A0A024R9I2 P08912 Q8IVW0	Q9HD19 Q9Y289
PDB IDs		6OL9
Enriched GO Terms of Interacting Partners?
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