CHRM5 and ATP9A

Data Source:
BioGRID (two hybrid)

		CHRM5	ATP9A
Description		cholinergic receptor muscarinic 5	ATPase phospholipid transporting 9A (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Dendrite Synapse Postsynaptic Membrane	Endosome Early Endosome Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Early Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity	Magnesium Ion Binding Protease Binding ATP Binding ATPase-coupled Intramembrane Lipid Transporter Activity
	Biological Process	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Endocytosis Phospholipid Translocation
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events	Ion transport by P-type ATPases
Drugs		Ziprasidone Amitriptyline Metixene Terfenadine Clozapine Doxylamine Trihexyphenidyl Loxapine Meperidine Imipramine Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Brompheniramine Maprotiline Methantheline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone Homatropine Thonzylamine Revefenacin Propiverine Rociverine Aripiprazole lauroxil
Diseases
GWAS		Malaria ( 31844061)	Metabolite levels ( 23823483) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		31 interacting genes: ASPH ASTN2 ATP2A2 ATP9A CBFB CD82 EPB41L1 EPC1 ERCC1 GJB6 GOLGA8A GPRASP1 HLA-F MAP3K1 MSMO1 MYH7 NLE1 NPAS3 PRSS16 REEP5 RGS7 RTN1 SLC2A6 SLC5A6 SLC6A8 SMAD6 SNCA SPNS1 STARD3NL TMEM161A USP33	1 interacting genes: CHRM5
Entrez ID		1133	10079
HPRD ID		00331	18541
Ensembl ID		ENSG00000184984	ENSG00000054793
Uniprot IDs		A0A024R9I2 P08912 Q8IVW0	B4DR18 O75110 Q2NLD0
PDB IDs		6OL9
Enriched GO Terms of Interacting Partners?
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