PARK7 and FADD

  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

PARK7

FADD

Description Parkinsonism associated deglycase Fas associated via death domain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Celiac disease ( 20190752)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Ischemic stroke ( 24262325)
  • Ulcerative colitis ( 28067908 21297633)
Interacting Genes 24 interacting genes: BAX BBS1 BCL2L1 CASP8 CSN1S1 DAXX EFCAB6 FADD GOPC GPX4 HIPK1 HSPA5 MAPK8IP1 MAPKAPK5 NDUFA4 PIAS2 PINK1 PPP2R1A PPP2R1B SNCA SOD1 SUMO1 UBA2 UBE2I 54 interacting genes: ABCA1 ANK3 ATG5 BTG1 CASP10 CASP8 CASP8AP2 CFLAR CSNK1A1 DAP3 DAPK1 DDIT4L DDX24 DEDD EDA2R FAF1 FAS FASLG HIPK3 IKBKG IRAK1 LRRCC1 MBD4 MKRN1 MOB4 MYD88 NACA NOL3 NUTM2F PARK7 PEA15 PIDD1 PIN1 PRKCZ PTPN13 RALBP1 RAP1A RIPK1 RNF4 RYBP SDCBP STAT1 STUB1 TAB1 TCEA2 TNFRSF10A TNFRSF10B TRADD TRAF2 TRIM21 UBE2I XPO5 ZCCHC12 ZMYM5
Entrez ID 11315 8772
HPRD ID 03961 03909
Ensembl ID ENSG00000116288 ENSG00000168040
Uniprot IDs Q99497 V9HWC2 Q13158
PDB IDs 1J42 1P5F 1PDV 1PDW 1PE0 1Q2U 1SOA 1UCF 2OR3 2R1T 2R1U 2R1V 2RK3 2RK4 2RK6 3B36 3B38 3B3A 3BWE 3CY6 3CYF 3CZ9 3CZA 3EZG 3F71 3SF8 4BTE 4MNT 4MTC 4N0M 4N12 4OGF 4OQ4 4P2G 4P34 4P35 4P36 4RKW 4RKY 4S0Z 4ZGG 5IP5 5SY6 5SY9 5SYA 6AF5 6AF7 6AF9 6AFA 6AFB 6AFC 6AFD 6AFE 6AFF 6AFG 6AFH 6AFI 6AFJ 6AFL 6E5Z 6M8Z 7C62 1A1W 1A1Z 1E3Y 1E41 2GF5 3EZQ 3OQ9 6ACI
Enriched GO Terms of Interacting Partners?
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