NRM and HDAC11

Data Source:
BioGRID (two hybrid)

		NRM	HDAC11
Description		nurim	histone deacetylase 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Histone Deacetylase Complex Nucleus Plasma Membrane
	Molecular Function	Molecular_function Protein Binding	Histone Deacetylase Activity Protein Binding Transcription Factor Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific)
	Biological Process	Biological_process	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation
Pathways			NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway
Drugs			Belinostat Panobinostat
Diseases
GWAS		Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)	Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 25673412) Ulcerative colitis ( 26278503)
Interacting Genes		50 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35C2 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59	7 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 NELFCD NRM PHYHIP
Entrez ID		11270	79885
HPRD ID		10120	09146
Ensembl ID		ENSG00000137404	ENSG00000163517
Uniprot IDs		A0A1U9X845 B3KQU6 Q8IXM6	B5MCQ6 E7ETT9 Q6IA14 Q96DB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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