NRM and PARP15

Data Source:
BioGRID (two hybrid)

		NRM	PARP15
Description		nurim	poly(ADP-ribose) polymerase family member 15
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nucleus Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Transcription Corepressor Activity NAD+ ADP-ribosyltransferase Activity Protein Binding NAD+ Binding Protein ADP-ribosylase Activity
	Biological Process	Biological_process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression Protein Poly-ADP-ribosylation Protein Mono-ADP-ribosylation
Pathways
Drugs			N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Diseases
GWAS		Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)	Major depressive disorder ( 22472876) Periodontitis (CDC/AAP) ( 24024966)
Interacting Genes		50 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35C2 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59	2 interacting genes: APP NRM
Entrez ID		11270	165631
HPRD ID		10120	08811
Ensembl ID		ENSG00000137404	ENSG00000173200
Uniprot IDs		A0A1U9X845 B3KQU6 Q8IXM6	B7ZL48 C9J7L3 Q460N3
PDB IDs			3BLJ 3GEY 3V2B 4F0E 6EK3 6RY4
Enriched GO Terms of Interacting Partners?
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