FAM107A and RNLS

Data Source:
BioGRID (two hybrid)

		FAM107A	RNLS
Description		family with sequence similarity 107 member A	renalase, FAD dependent amine oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton Nuclear Speck Ruffle Membrane Neuron Projection Synapse	Extracellular Region Extracellular Space
	Molecular Function	Molecular_function Actin Binding Protein Binding	Protein Binding Oxidoreductase Activity, Acting On NAD(P)H Epinephrine Binding NADH Binding Monoamine Oxidase Activity
	Biological Process	Regulation Of Cell Growth Cell Cycle Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Response To Ischemia Negative Regulation Of Heart Rate NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Blood Pressure Response To Epinephrine Response To Salt
Pathways			Nicotinamide salvaging
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)	Birth weight ( 31043758) Cortical amyloid beta load ( 29860282) Depressive and manic episodes in bipolar disorder ( 26297903) End stage renal disease in APOL1 risk genotype-negative individuals ( 29885931) Estimated glomerular filtration rate in coronary artery disease and impaired kidney function ( 30809046) Familial lung adenocarcinoma ( 29924316) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mercury levels ( 26025379) Prostate cancer ( 29892016) Pulse pressure ( 27841878) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Thyroid stimulating hormone levels ( 32769997) Type 1 diabetes ( 30659077 30572963) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47	2 interacting genes: FAM107A MAST1
Entrez ID		11170	55328
HPRD ID		09753	07742
Ensembl ID		ENSG00000168309	ENSG00000184719
Uniprot IDs		A0A024R327 O95990 Q6IAM1	B4DJW3 Q5VYX0
PDB IDs			3QJ4
Enriched GO Terms of Interacting Partners?
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