FAM107A and CPSF3

Data Source:
BioGRID (two hybrid)

		FAM107A	CPSF3
Description		family with sequence similarity 107 member A	cleavage and polyadenylation specific factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton Nuclear Speck Ruffle Membrane Neuron Projection Synapse	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Molecular_function Actin Binding Protein Binding	RNA Binding Endoribonuclease Activity Protein Binding 5'-3' Exonuclease Activity Metal Ion Binding
	Biological Process	Regulation Of Cell Growth Cell Cycle Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage MRNA 3'-end Processing By Stem-loop Binding And Cleavage MRNA Export From Nucleus MRNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47	9 interacting genes: CLP1 FAM107A HSPB1 MIR19A MIR19B1 MIR92A2 PAPOLA POLR2A YWHAG
Entrez ID		11170	51692
HPRD ID		09753	05825
Ensembl ID		ENSG00000168309	ENSG00000119203
Uniprot IDs		A0A024R327 O95990 Q6IAM1	G5E9W3 Q9UKF6
PDB IDs			2I7T 2I7V 6M8Q 6V4X
Enriched GO Terms of Interacting Partners?
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