CLP1 and PRR3

Data Source:
BioGRID (two hybrid)

		CLP1	PRR3
Description		cleavage factor polyribonucleotide kinase subunit 1	proline rich 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytosol MRNA Cleavage Factor Complex
	Molecular Function	Protein Binding ATP Binding ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity Polydeoxyribonucleotide Kinase Activity ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Processing Phosphorylation Cerebellar Cortex Development Targeting Of MRNA For Destruction Involved In RNA Interference MRNA 3'-end Processing SiRNA Loading Onto RISC Involved In RNA Interference
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 29255261) Schizophrenia ( 25056061 29483656)	Autism spectrum disorder or schizophrenia ( 28540026) Itch intensity from mosquito bite ( 28199695) Neuroticism ( 29255261)
Interacting Genes		17 interacting genes: APP CCDC130 CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 TSEN54	21 interacting genes: APOBEC3C ASF1A BCL2L2-PABPN1 CCDC57 CLP1 HNRNPK KHDRBS2 KHDRBS3 KLF1 KRTAP6-2 KRTAP6-3 MYPOP NXF1 PSMA3 RAMAC RBM3 RBMX RBMY1A1 RBMY1F RBMY1J TLE5
Entrez ID		10978	80742
HPRD ID		16382	17915
Ensembl ID		ENSG00000172409	ENSG00000204576
Uniprot IDs		Q92989	B3KQA4 P79522 Q96QB9
PDB IDs
Enriched GO Terms of Interacting Partners?
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