UQCR11 and TUBB4A

Data Source:
BioGRID (affinity chromatography technology)

		UQCR11	TUBB4A
Description		ubiquinol-cytochrome c reductase, complex III subunit XI	tubulin beta 4A class IVa
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane Respirasome	Nucleus Cytoplasm Cytosol Microtubule Axoneme Internode Region Of Axon Neuronal Cell Body Myelin Sheath Extracellular Exosome
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity Electron Transfer Activity	GTPase Activity Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding GTP Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Mitochondrial Electron Transport, Ubiquinol To Cytochrome C	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Microtubule Polymerization Ciliary Basal Body-plasma Membrane Docking
Pathways		Respiratory electron transport	Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Anchoring of the basal body to the plasma membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs		6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2	Epothilone D Patupilone CYT997 ZEN-012 Artenimol
Diseases
GWAS			Left-handedness ( 32989287)
Interacting Genes		1 interacting genes: WNT2	10 interacting genes: BMPR2 CLN8 LINC01554 NEAT1 NR4A1 SELENOF STAU1 STK11 SUMO2 YWHAG
Entrez ID		10975	10382
HPRD ID		15628	04045
Ensembl ID		ENSG00000127540	ENSG00000104833
Uniprot IDs		O14957	P04350
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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