TUBB4A and SELENOF

Data Source:
BioGRID (two hybrid)

		TUBB4A	SELENOF
Description		tubulin beta 4A class IVa	selenoprotein F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Microtubule Axoneme Internode Region Of Axon Neuronal Cell Body Myelin Sheath Extracellular Exosome	Endoplasmic Reticulum Lumen
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding GTP Binding	Protein Binding Oxidoreductase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Microtubule Polymerization Ciliary Basal Body-plasma Membrane Docking	'de Novo' Posttranslational Protein Folding
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Anchoring of the basal body to the plasma membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs		Epothilone D Patupilone CYT997 ZEN-012 Artenimol
Diseases
GWAS		Left-handedness ( 32989287)
Interacting Genes		10 interacting genes: BMPR2 CLN8 LINC01554 NEAT1 NR4A1 SELENOF STAU1 STK11 SUMO2 YWHAG	8 interacting genes: AGTR1 BAMBI RDH11 SEPTIN3 TUBB4A UGGT1 UGGT2 XRCC6
Entrez ID		10382	9403
HPRD ID		04045	09376
Ensembl ID		ENSG00000104833	ENSG00000183291
Uniprot IDs		P04350	O60613
PDB IDs
Enriched GO Terms of Interacting Partners?
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