UQCR11 and WNT2

Data Source:
BioGRID (two hybrid)

		UQCR11	WNT2
Description		ubiquinol-cytochrome c reductase, complex III subunit XI	Wnt family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane Respirasome	Extracellular Region Extracellular Space Cytoplasm Extrinsic Component Of External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Wnt Signalosome
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity Electron Transfer Activity	Frizzled Binding Cytokine Activity Protein Binding Receptor Ligand Activity
	Biological Process	Generation Of Precursor Metabolites And Energy Mitochondrial Electron Transport, Ubiquinol To Cytochrome C	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Mesenchymal Cell Proliferation Lens Development In Camera-type Eye Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Wnt Signaling Pathway Neurogenesis Neuron Differentiation Lung Development Cell Proliferation In Midbrain Cell Fate Commitment Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Atrial Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Cardiac Muscle Cell Proliferation Canonical Wnt Signaling Pathway Cardiac Epithelial To Mesenchymal Transition Lung Induction Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Labyrinthine Layer Blood Vessel Development Iris Morphogenesis Mammary Gland Epithelium Development Cellular Response To Retinoic Acid Cellular Response To Transforming Growth Factor Beta Stimulus Midbrain Dopaminergic Neuron Differentiation Canonical Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation
Pathways		Respiratory electron transport	WNT ligand biogenesis and trafficking WNT ligand biogenesis and trafficking Class B/2 (Secretin family receptors)
Drugs		6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS			Dupuytren's disease ( 28886342 21732829) Inflammatory bowel disease ( 28067908) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573) Tonsillectomy ( 27182965 28928442) Ulcerative colitis ( 28067908) Uterine fibroids ( 31649266)
Interacting Genes		1 interacting genes: WNT2	8 interacting genes: AQP5 FZD1 FZD9 HCK RRAGC SFRP1 UQCR11 WNT3A
Entrez ID		10975	7472
HPRD ID		15628	00999
Ensembl ID		ENSG00000127540	ENSG00000105989
Uniprot IDs		O14957	A0A384MDX3 P09544
PDB IDs		5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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