BRD8 and MIS18A

Data Source:
BioGRID (two hybrid)

		BRD8	MIS18A
Description		bromodomain containing 8	MIS18 kinetochore protein A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division
Pathways		HATs acetylate histones	Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)
Interacting Genes		12 interacting genes: AGTR1 EP400 FSD2 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1	30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655
Entrez ID		10902	54069
HPRD ID		04166	10749
Ensembl ID		ENSG00000112983	ENSG00000159055
Uniprot IDs		B4DEG9 B4DMS9 B4DN43 Q9H0E9	Q9NYP9
PDB IDs
Enriched GO Terms of Interacting Partners?
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