USP20 and ZNF343

Data Source:
BioGRID (two hybrid)

		USP20	ZNF343
Description		ubiquitin specific peptidase 20	zinc finger protein 343
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		Ub-specific processing proteases	Generic Transcription Pathway
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Conotruncal heart defects (maternal effects) ( 28468790) Glomerular filtration rate in chronic kidney disease ( 26420894)
Interacting Genes		69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB	23 interacting genes: ACTN3 APP BFSP2 CCDC125 FAM90A1 JRK KLC4 NEK6 NME7 NUDT22 NXF1 PAX9 RAD51D RUNX1T1 SDCBP STK16 TEPSIN TRIM41 UBQLN1 USP20 ZNF319 ZNF648 ZNF835
Entrez ID		10868	79175
HPRD ID		07505	18327
Ensembl ID		ENSG00000136878	ENSG00000088876
Uniprot IDs		Q9Y2K6	A0A087WZQ2 Q6P1L6
PDB IDs		6KCZ
Enriched GO Terms of Interacting Partners?
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