TUBGCP2 and PCNT

Data Source:
HPRD (in vivo)

		TUBGCP2	PCNT
Description		tubulin gamma complex associated protein 2	pericentrin
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Equatorial Microtubule Organizing Center Gamma-tubulin Complex Nucleoplasm Centrosome Microtubule Organizing Center Cytosol Cytoplasmic Microtubule Gamma-tubulin Small Complex Membrane	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite
	Molecular Function	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Protein Binding Calmodulin Binding Molecular Adaptor Activity
	Biological Process	Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases			Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)	Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Treatment resistant depression ( 30468137)
Interacting Genes		3 interacting genes: KIF14 PCNT UBC	11 interacting genes: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID		10844	5116
HPRD ID		18245	05804
Ensembl ID		ENSG00000130640	ENSG00000160299
Uniprot IDs		Q53EQ3 Q9BSJ2	O95613
PDB IDs		6V6B 6V6S 6X0V
Enriched GO Terms of Interacting Partners?
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