POLR3C and GTF3C4

Data Source:
HPRD (in vitro, in vivo)

		POLR3C	GTF3C4
Description		RNA polymerase III subunit C	general transcription factor IIIC subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion
	Molecular Function	Single-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD PAX6 PICK1 PNMA5 POLR3G POLR3GL POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN	13 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F SUMO2 TBP
Entrez ID		10623	9329
HPRD ID		17880	11998
Ensembl ID		ENSG00000186141	ENSG00000125484
Uniprot IDs		Q9BUI4	B3KNH2 Q9UKN8
PDB IDs		2XUB 2XV4 5AFQ
Enriched GO Terms of Interacting Partners?
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