POLR3C and VRTN

Data Source:
BioGRID (two hybrid)

		POLR3C	VRTN
Description		RNA polymerase III subunit C	vertebrae development associated
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol	Chromatin
	Molecular Function	Single-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding	Transposase Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus	Transposition, DNA-mediated Regulation Of Transcription By RNA Polymerase II
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS			FEV1 ( 30804560) Lung function (FVC) ( 30804560) Refractive error ( 32231278)
Interacting Genes		39 interacting genes: ANKRD23 APP CAMK2B CEP44 CEP63 COIL DISC1 ENKD1 GOLGA2 GTF3C4 HAUS1 INCA1 KATNBL1 KIAA0408 KLHL2 KPNA1 KPNA3 KPNA5 KPNA6 KRT75 LZTS1 NCKIPSD PAX6 PICK1 PNMA5 POLR3G POLR3GL POU6F2 PRDM16 RBBP8NL ROCK1 ROPN1 SP100 TNR TRAF2 TRIM27 UBXN1 VAX1 VRTN	10 interacting genes: C9orf72 CTBP2 EIF4A3 FAM90A1 POLR3C RAB2B RAB3A RAB3B RAB3C RAB3D
Entrez ID		10623	55237
HPRD ID		17880	16593
Ensembl ID		ENSG00000186141	ENSG00000133980
Uniprot IDs		Q9BUI4	Q9H8Y1
PDB IDs		2XUB 2XV4 5AFQ
Enriched GO Terms of Interacting Partners?
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