POLR3F and WDR89

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR3F	WDR89
Description		RNA polymerase III subunit F	WD repeat domain 89
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm RNA Polymerase III Complex Cytosol
	Molecular Function	Double-stranded DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase III Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		15 interacting genes: ATPAF2 BDP1 BRF1 ERG28 GTF3C4 KAT5 LRIF1 PRPF4B RIN3 STC2 SUV39H2 TBP TNS2 UBE2G2 WDR89	5 interacting genes: APP PHYHIP POLR2M POLR3F SOCS6
Entrez ID		10621	112840
HPRD ID		15156	12635
Ensembl ID		ENSG00000132664	ENSG00000140006
Uniprot IDs		Q05DB8 Q9H1D9	A0A024R667 Q96FK6
PDB IDs		2DK5 2YU3
Enriched GO Terms of Interacting Partners?
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