TRIM3 and KCTD7

Data Source:
BioGRID (two hybrid)

		TRIM3	KCTD7
Description		tripartite motif containing 3	potassium channel tetramerization domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Golgi Apparatus Dendrite	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Nervous System Development Protein Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Positive Regulation Of Transporter Activity Post-translational Protein Modification Protein Homooligomerization Membrane Hyperpolarization Glutamate Homeostasis
Pathways		Interferon gamma signaling	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Malaria ( 31844061)	Aortic root size ( 21223598) Cotinine glucuronidation ( 25293881) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		30 interacting genes: ACTN4 ASL CDKN1A CEP70 CSNK1D CSNK1E KCTD7 KIF21B LNX1 LRRC8E MYO5A MYO5B ROPN1 TEAD1 TEAD2 TNFAIP3 TPTEP2-CSNK1E TRIM2 TRIM21 UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2G2 UBE2I UBE2K UBE2U UBE2Z USP32	41 interacting genes: ADAMTSL4 ATXN7L2 BAG4 CUL3 DVL3 EFHC2 GAS2L2 GORASP2 INCA1 INO80B KAT5 KRT75 KRTAP13-3 LNX1 MDFI MEOX1 MEOX2 NIF3L1 NTAQ1 NXF1 PARVG PAX6 PIN1 PPARA PRPF18 PRR22 PSMA1 RAB4A REL TCEA2 TCEANC TERF1 TRIM2 TRIM3 UBC VEZF1 ZNF417 ZNF438 ZNF474 ZNF552 ZNF587
Entrez ID		10612	154881
HPRD ID		05690	13770
Ensembl ID		ENSG00000110171	ENSG00000243335
Uniprot IDs		B7Z5Y8 O75382	A0A024RDN7 Q96MP8
PDB IDs
Enriched GO Terms of Interacting Partners?
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