DRAP1 and DR1

Data Source:
HPRD (in vivo, in vitro)

		DRAP1	DR1
Description		DR1 associated protein 1	down-regulator of transcription 1
Image
GO Annotations	Cellular Component	Nucleus Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex	Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Negative Cofactor 2 Complex RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Core Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Histone H3 Acetylation Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly
Pathways		Signaling by NODAL Signaling by Activin	HATs acetylate histones
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Eosinophil percentage of granulocytes ( 27863252) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252) Severe influenza A (H1N1) infection ( 26379185)	Apolipoprotein A1 levels ( 32203549) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Red blood cell count ( 32888494) Triglyceride levels ( 32203549 29403010) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31578528)
Interacting Genes		31 interacting genes: APP ARHGEF10L CDKN2C DNAJB11 DR1 FBXO7 FEZ1 FEZ2 FOXH1 GTF2B LMO2 LNX1 LNX2 MCRS1 MORF4L1 NCK2 NFYB PICK1 PIK3R3 PLEKHF2 POLE3 RPL9 SDCBP SRPK2 TAF9 TAF9B TBP TK1 TNFRSF14 TTF2 ZEB1	9 interacting genes: DNMT3L DRAP1 NFIL3 NFYC POLE3 TBP XPO1 YEATS2 ZDHHC17
Entrez ID		10589	1810
HPRD ID		03796	03284
Ensembl ID		ENSG00000175550	ENSG00000117505
Uniprot IDs		Q14919	Q01658 Q658N3
PDB IDs		1JFI	1JFI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?