TXNRD2 and BCAS2

Data Source:
BioGRID (pull down)

		TXNRD2	BCAS2
Description		thioredoxin reductase 2	BCAS2 pre-mRNA processing factor
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Centrosome Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Flavin Adenine Dinucleotide Binding	Protein Binding
	Biological Process	Response To Oxygen Radical Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing
Pathways		Detoxification of Reactive Oxygen Species	mRNA Splicing - Major Pathway
Drugs		Motexafin gadolinium
Diseases
GWAS		Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary angle closure) ( 22922875) Glaucoma (primary open-angle) ( 26752265 29891935) Intraocular pressure ( 29785010 31959993 30054594) Lean body mass ( 28552196) Staphylococcus aureus infection ( 24847357)	Autism ( 24189344) Chronotype ( 30696823)
Interacting Genes		7 interacting genes: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3	61 interacting genes: ACY1 AIMP2 BLK C10orf82 C9orf24 CCDC120 CCDC17 ECM1 EMILIN3 ENKD1 EP300 ESR1 ESR2 FAM86C1P GOLGA2 HGS HSF2BP IFI35 IKZF3 KRT20 KRT27 KRT31 KRT34 KRT35 KRT36 KRT37 KRT40 KRT75 KRTAP19-6 KRTAP8-1 LMO1 LMO2 LMO3 LMO4 MED29 MIIP MYOZ3 OIP5 PAX5 PCBD2 PFDN5 PGR PLAGL2 PLEKHF2 POT1 PPARG PPP1R32 SF1 SMARCD1 SNRNP200 SNRPC TCF4 TCHP TP53BP2 TRAF1 TXN2 TXNRD2 UBC USHBP1 YPEL3 ZWINT
Entrez ID		10587	10286
HPRD ID		18519	05777
Ensembl ID		ENSG00000184470	ENSG00000116752
Uniprot IDs		E7EWK1 Q9NNW7	B2R7W3 O75934
PDB IDs		1W1E	5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P
Enriched GO Terms of Interacting Partners?
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