PRDX4 and SULT2A1

Data Source:
BioGRID (two hybrid)

		PRDX4	SULT2A1
Description		peroxiredoxin 4	sulfotransferase family 2A member 1
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GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cytoplasm Cytosol
	Molecular Function	Protein Binding Thioredoxin Peroxidase Activity	Alcohol Sulfotransferase Activity Protein Binding Sulfotransferase Activity Bile-salt Sulfotransferase Activity Steroid Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding
	Biological Process	Response To Oxidative Stress I-kappaB Phosphorylation Spermatogenesis Male Gonad Development Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Cellular Response To Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Male Germ Cell Proliferation	Ethanol Catabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Catabolic Process Regulation Of Lipid Metabolic Process Bile Acid Catabolic Process Thyroid Hormone Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		Neutrophil degranulation	Cytosolic sulfonation of small molecules PPARA activates gene expression
Drugs			Adenosine 3',5'-diphosphate Aetiocholanolone Mercuric iodide
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 30072576) Cleft palate ( 30452639) Dehydroepiandrosterone sulphate levels ( 21533175) Gallstone disease ( 30504769 27094239) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Triglyceride levels ( 32203549) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		25 interacting genes: A1BG ALG12 APOB CFHR1 CFHR3 CLIC1 CYP27A1 DUSP23 GLTPD2 HDAC6 LBP MAP4K2 MT-CO1 NR4A1 PLG PRDX1 PRDX2 PRDX3 RCHY1 SULT2A1 SUMO4 TBXA2R TTF2 UBC VTN	6 interacting genes: NIF3L1 PRDX4 STAT3 STK3 SULT1B1 TMX1
Entrez ID		10549	6822
HPRD ID		05935	00502
Ensembl ID		ENSG00000123131	ENSG00000105398
Uniprot IDs		Q13162 V9HW63	A8K015 Q06520
PDB IDs		2PN8 3TJB 3TJF 3TJG 3TJJ 3TJK 3TKP 3TKQ 3TKR 3TKS 4RQX 5HQP	1EFH 1J99 1OV4 2QP3 2QP4 3F3Y 4IFB
Enriched GO Terms of Interacting Partners?
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