SEMA4F and NRP2

Data Source:
HPRD (in vitro)

		SEMA4F	NRP2
Description		ssemaphorin 4F	neuropilin 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Membrane Dendrite Perikaryon Postsynaptic Membrane	Semaphorin Receptor Complex Extracellular Region Plasma Membrane Membrane Integral Component Of Membrane Axon Glutamatergic Synapse Integral Component Of Postsynaptic Membrane
	Molecular Function	Semaphorin Receptor Binding Chemorepellent Activity	Vascular Endothelial Growth Factor-activated Receptor Activity Protein Binding Heparin Binding Semaphorin Receptor Activity Growth Factor Binding Cytokine Binding Signaling Receptor Activity Metal Ion Binding
	Biological Process	Neural Crest Cell Migration Cell-cell Signaling Nervous System Development Axon Guidance Positive Regulation Of Cell Migration Retinal Ganglion Cell Axon Guidance Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Semaphorin-plexin Signaling Pathway	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Outflow Tract Septum Morphogenesis Cell Adhesion Axon Guidance Positive Regulation Of Endothelial Cell Migration Viral Process Facial Nerve Structural Organization Vestibulocochlear Nerve Structural Organization Nerve Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Ventral Trunk Neural Crest Cell Migration Vascular Endothelial Growth Factor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Extension Involved In Axon Guidance Negative Chemotaxis Sympathetic Ganglion Development Trigeminal Ganglion Development Sensory Neuron Axon Guidance Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Regulation Of Postsynapse Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Facioacoustic Ganglion Development Dorsal Root Ganglion Morphogenesis Cellular Response To Leukemia Inhibitory Factor
Pathways			Neurophilin interactions with VEGF and VEGFR NrCAM interactions
Drugs
Diseases
GWAS		Myopia (pathological) ( 22685421)	Blood protein levels ( 30072576 29875488) Craniofacial microsomia ( 26853712) Diisocyanate-induced asthma ( 25918132) Neuropathy x type 2 diabetes interaction ( 32541925)
Interacting Genes		2 interacting genes: DLG4 NRP2	11 interacting genes: FLT1 L1CAM NRP1 PGF PLXNA1 PLXNB1 SEMA3B SEMA3C SEMA3F SEMA4F VEGFA
Entrez ID		10505	8828
HPRD ID		04748	03643
Ensembl ID		ENSG00000135622	ENSG00000118257
Uniprot IDs		A0A087WYZ7 O95754	O60462 Q7Z3T9
PDB IDs			2QQJ 2QQK 2QQL 2QQO 4QDQ 4QDR 4QDS 5DN2 5DQ0 6GH8
Enriched GO Terms of Interacting Partners?
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