TAB1 and TOM1

  • Data Source:
  • BioGRID (biochemical)

TAB1

TOM1

Description TGF-beta activated kinase 1 (MAP3K7) binding protein 1 target of myb1 membrane trafficking protein
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Factor VIII levels ( 30586737)
  • IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392)
  • IgG digalactosylation phenotypes (multivariate analysis) ( 28878392)
  • IgG disialylation phenotypes (multivariate analysis) ( 28878392)
  • IgG fucosylation phenotypes (multivariate analysis) ( 28878392)
  • IgG galactosylation phenotypes (multivariate analysis) ( 28878392)
  • IgG glycosylation ( 23382691)
  • IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392)
  • IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392)
  • IgG sialylation phenotypes (multivariate analysis) ( 28878392)
  • Inflammatory bowel disease ( 23128233)
  • Intelligence (MTAG) ( 29326435)
  • Schizophrenia ( 29483656)
  • Sleep duration (short sleep) ( 30846698)
  • vWF levels ( 30586737)
  • Waist circumference ( 28552196)
  • Cholesterol, total ( 24097068)
  • HDL cholesterol ( 29404214)
  • High density lipoprotein cholesterol levels ( 31217584)
  • Hippocampal volume in mild cognitive impairment ( 29274321)
  • Inflammatory bowel disease ( 28067908)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Multiple myeloma ( 26007630)
  • Multiple myeloma and monoclonal gammopathy ( 26007630)
  • Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315)
  • Total cholesterol levels ( 28334899)
  • Ulcerative colitis ( 28067908)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 74 interacting genes: AATK ACAP3 ARAP1 ASRGL1 BMPR1A C9orf78 CARD11 CASP6 CDK5RAP3 CFL1 CKB CORO1A DBN1 DVL2 EGFR EPRS1 ERBB4 FADD FN1 GIT1 HNRNPR IKBKG ITCH KIFC2 LAP3 LCMT1 LGALS7 LGALS7B LNX2 MAP3K1 MAP3K7 MAPK11 MAPK14 MAPKAPK5 MICAL1 MON1A MTG2 NR2C2 NXPH3 OGT PDCD6IP PHACTR3 PHC2 POLDIP2 POLR3D PPP1R7 PPP2CB PPP2R1A PRKAR1A PTPMT1 RBX1 ROR2 RPL10 RPLP1 SERPINA4 SMAD6 SMAD7 SMURF1 SNRNP35 TAB2 TAB3 TRAF2 TRAF6 TRIP6 TRPC4AP TSSC4 UBC URB1 WDCP WTAP XIAP XPO7 YWHAG ZMYND11 21 interacting genes: APP CLTC DAZAP2 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 PILRA PTBP2 RPS27 SMURF1 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B
Entrez ID 10454 10043
HPRD ID 04012 05265
Ensembl ID ENSG00000100324 ENSG00000100284
Uniprot IDs A8K6K3 Q15750 B3KUF5 O60784
PDB IDs 2J4O 2POM 2POP 2YDS 2YIY 4AY5 4AY6 4GS6 4KA3 4L3P 4L52 4L53 4O91 5DIY 5E7R 5GJD 5GJF 5GJG 5J7S 5J8I 5J9L 5JGA 5JGB 5JGD 5JH6 5JK3 5NZZ 5O90 5V5N 5VVU 1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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