TOM1 and LRRC20

Data Source:
BioGRID (two hybrid)

		TOM1	LRRC20
Description		target of myb1 membrane trafficking protein	leucine rich repeat containing 20
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding Clathrin Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Signal Transduction Protein Transport Endosomal Transport Neutrophil Degranulation
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Low density lipoprotein cholesterol levels ( 32154731) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Brain connectivity ( 23471985) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		21 interacting genes: APP CLTC DAZAP2 EEA1 ILVBL LITAF LRRC20 MAP3K1 MYO6 NAA11 NEDD4 PILRA PTBP2 RPS27 SMURF1 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B	3 interacting genes: FBXO7 TOM1 ZBED1
Entrez ID		10043	55222
HPRD ID		05265	14314
Ensembl ID		ENSG00000100284	ENSG00000172731
Uniprot IDs		B3KUF5 O60784	A0A024QZL5 A0A024QZM2 A0A024QZR0 A0A0A0MS58 Q8TCA0
PDB IDs		1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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