UBAC1 and SPART

Data Source:
BioGRID (two hybrid)

		UBAC1	SPART
Description		UBA domain containing 1	spartin
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GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Cytoplasm Mitochondrial Outer Membrane Lipid Droplet Cytosol Plasma Membrane Midbody Synapse
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Ubiquitination	Abscission Negative Regulation Of BMP Signaling Pathway Lipid Droplet Organization Negative Regulation Of Collateral Sprouting In Absence Of Injury Neuromuscular Process Cell Division Regulation Of Mitochondrial Membrane Potential Adipose Tissue Development
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Ulcerative colitis ( 28067908)
Interacting Genes		34 interacting genes: AIRE APP ARRDC3 CCDC138 CDKN1B CPSF6 CSNK2A1 DAZAP2 DVL2 FAM168A HOXA2 HTT IGFBP6 LAPTM5 MAP3K1 MCM10 MGAT3 NEDD4L PLAAT2 PLEKHB2 POU6F2 PPP1CB RNF11 RNF123 RNF216 SMURF1 SPART TRIM2 TRIM39 UBB UBC UBQLN2 ZDHHC17 ZG16B	22 interacting genes: APP APPL1 DESI2 EPN2 EPS15 GPR35 ITCH MAP3K1 OTUB2 OTUD7B OTULIN PLIN3 PRKAR1A RABGEF1 SMURF1 SMURF2 TUBA1A UBAC1 USP5 WWP2 YOD1 ZFYVE9
Entrez ID		10422	23111
HPRD ID		12170	06170
Ensembl ID		ENSG00000130560	ENSG00000133104
Uniprot IDs		A0A140VK64 Q9BSL1	A0A024RDV9 Q8N0X7
PDB IDs		2DAI	2DL1 4U7I
Enriched GO Terms of Interacting Partners?
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